SUMMARY: ROYAL CANIN Veterinary DietTM/MC canine MOBILITY SUPPORT JS 21TM/MC is formulated for the adult dog and contains a unique ingredient, Green-Lipped Mussel Powder (Perna canaliculus), to help promote joint health. This food has been manufactured with a patented process to ensure the efficacy of this ingredient.

INDICATIONS:

CONTRAINDICATIONS:
-- For adult dogs with degenerative joint disease (osteoarthritis)
--
Growing puppies
-- For dogs at risk of developing degenerative joint disease
--
Pregnant or lactating bitches
-- Risk factors include:    
  -- Obesity    
  -- Advanced age    
  -- Very active lifestyle (i.e., working dogs, hunting dogs)    
  -- Large and giant breeds    
  -- History of joint injury or trauma    
  -- Genetic pre-disposition    


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RATIONALE:
Joint disease is common in older pets, especially in overweight dogs of the large or giant breeds. Green-Lipped Mussel Powder (GLMP) from Perna canaliculus is an ingredient that has been studied for its unique ability to promote joint health.

Although it is not clear which components of GLMP are responsible for its unique properties, GLMP is known to contain many constituents which may contribute to improved joint function. These constituents include several anti-inflammatory fatty acids [eicosatetraenoic acid (ETA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)], chondroitin sulfate (a glycosaminoglycan constituent of cartilage), glutamine (a glycosaminoglycan precursor), antioxidants, and antioxidant co-factor minerals (zinc, copper, and manganese).

Clinical studies have shown that GLMP significantly improves overall arthritic scores, joint pain, and joint swelling in dogs with clinical signs of osteoarthritis. MOBILITY SUPPORT JS 21TM/MC has a slightly restricted calorie content to help control weight in less active dogs easing stress on their joints. It is antioxidant enriched to help maintain the dog’s natural defense system and help fight the effects of oxidative damage and the production of free radicals. The GLMP used in MOBILITY SUPPORT JS 21TM/MC is obtained from farm-raised mussels in New Zealand and is incorporated into the diet using a patented process to ensure delivery of this ingredient in the finished pet food.


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REFERENCES:
Bui LM,, Bierer TL. The influence of green-lipped mussels (Perna canaliculus). Veterinary Therapeutics 2:101-111, 2001.

Bui LM., Bierer TL. Changes in blood minerals, antioxidants and fatty acids in dogs fed green-lipped mussel (Perna canaliculus). FASEB J 14(4): A749-521.11, 2000.

Bui LM,, Pawlowski K., Bierer TL. The influence of green-lipped mussel powder (Perna canaliculus) on alleviating arthritic signs in dogs (abstract). FASEB J 14(4): A218, 2000.

Bui LM, Pawlowsk, K, Bierer T. A semi-moist treat containing green-lipped mussel (Perna canaliculus) can help alleviate arthritic signs in dogs (abstract). FASEB J 14(4): A748, 2000..

Bui LM. Arthritis management in dogs through diet. Waltham Focus 10(2): 32-33, 2000.

Bui LM, Pawlowski K, Bierer TL. Improvement of arthritic symptoms in dogs fed green-lipped mussel (Perna canaliculus). Waltham International Symposium-Pet Nutrition Coming of Age-Canada:23, 2001.

Bui LM, Taylor F. Nutritional Management of arthritis in dogs. Waltham Focus–Advances in Clinical Nutrition 10(2): 64-69, 2000.

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